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Lexapro 5 mg tablet Product Information Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:71133-201 Route of Administration ORAL DEA Schedule CII Active Ingredient/Active Moiety Ingredient Name Basis of Strength lisdexamfetamine dimesylate (ld) 50 mg Inactive Ingredients Ingredient Name Strength CAS # 123496-89-7 METHYLCYCLINE HYDROXYSTATINIBISAMIDE DIMETHICONE, NICOLEMETHYLTRIAMINODIMETHYLESIATE LYSIDE, METHYLPARABEN Lisdexamfetamine dimesylate is a CNS stimulant that increases the rate and concentration of dopamine release in the brain. It should be noted that the CNS effects of lisdexamfetamine can be dose dependent and may dose-proscribed [see DOSAGE ADMINISTRATION]. The most common adverse reactions associated with administration of lisdexamfetamine dimesylate are: Decreased appetite and changes in mood, especially elderly individuals who take large amounts of lisdexamfetamine dimesylate. The most common adverse reaction is decreased appetite which most commonly due to lack of caloric intake. Patients should be advised to take a meal as soon possible following administration of lisdexamfetamine dimesylate [see ADVERSE REACTIONS]. Increased blood pressure. The most common adverse reactions associated with administration of lisdexamfetamine dimesylate may include: Anaphylaxis. Cerebral edema. Deafness. Decreased attention span. Decreased mental alertness. Depression. Dyskinesia. Increased body temperature. Increased appetite. Increased thirst. Increased urination. Nervousness. Vomiting. Increased sensitivity to noise and light. In most patients, adverse reactions these categories are of short duration and do not usually require additional treatment. However, in more patients, changes mental state may require hospitalization and treatment with hypnotics or psychotropic drugs. Patients should be advised that the increased potency of lisdexamfetamine dimesylate may be associated with an increased risk of seizures. Lisdexamfetamine dimesylate has been used in the treatment of attention deficit/hyperactivity disorder (ADHD) and related conditions for approximately 20 years. However, there is currently no scientific evidence to support its effectiveness in treating attention deficit hyperactivity disorder, narcolepsy, or other stimulant-induced mental disorders (for example, attention-deficit hyperactivity disorder, narcolepsy, disorder not otherwise specified and/or obsessive-compulsive disorder). Lisdexamfetamine dimesylate should be used cautiously in pediatric patients of any age due to its potential for drowsiness, sedation, respiratory depression, and cardiac/thoracic toxicity. Pediatric users of lisdexamfetamine dimesylate should be monitored closely. Geriatric use: The pharmacokinetics have been compared between elderly patients and children there is no evidence.

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